Using these Runes in combat uses Focus.

Runes will vary in function and can even come already equipped to certain weapons.

Alternatively, you’re free to buy Runes fromEleanor the enchanter in Sacrament.

Screenshot of Eleanor in No Rest For The Wicked, the enchantment merchant.

This is the main town you’ll visit first inNo Rest For The Wickedwhere several merchants offer different services.

you’re able to find Eleanor located in theMerchant square, as seen on the map above.

you’re able to alsoextract Runesin this menu.

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In doing so, you’lldestroy the weaponthe Rune was originally in, however.

In doing so, you willincrease the rarityof the item.

It is not possible to gain a unique weapon or piece of armour through enchanting.

Screenshot of Eleanor’s map location in No Rest For The Wicked, the enchantment merchant.

These are usually picked up from boss fights.

you’re free to apply these Runes to your offhand by pressing the R key.

In combat, press the number key that corresponds to the Rune you wish to cast.

Screenshot of Gems in No Rest For The Wicked.

You’ll notice awhite ringaround the Rune that is currently equipped in the bottom left corner of your screen.

Now, to cast the Rune,right-click.

That rounds off our guide to Runes in No Rest For The Wicked.

Screenshot of Rune extraction in No Rest For The Wicked.

Screenshot of a gold unique weapon in No Rest For The Wicked.

Screenshot of spall casting instructions in No Rest For The Wicked.