The game will issue a pop-up with a few bits of information regarding the disease.
If it becomes too late, your Pawn will go completely crazy and will likely kill an entire village.
It is possible to recruit a Pawn with Dragonsplague without knowing.

The disease has an incubation period that takes days to present itself.
Rather, if you suspect your Pawn of having the plagueyou’ll need to kill them.
The downside to this is that it will slightly lower yourMain Pawn’s affinitywith your Arisen.

If Dragonsplague results in NPC deaths, you might revive any NPC with aWakestone.
you’re free to alsouse the Eternal Wakestoneto revive multiple NPCs at once.
This is a one-use item and worth saving for such a scenario.

you’re able to get the Eternal Wakestone by defeating the Sphinx.
Once present in your party, the plague may jump from Pawn to Pawn.
This usually happens when you rest at a campfire.

As discussed, due to the incubation period you canhire Pawns that already have it.
Your Main Pawn may also return from aPawn questwith it.
Some players also report contracting Dragonsplague after fighting Drakes (lesser Dragons).
Specifically,when Pawns grapple Drakes.
Others may never get it during a playthrough.
That rounds off our guide to Dragonsplague in Dragon’s Dogma 2.